Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Cystinuria in a maned wolf

M Bush, K C Bovee

Journal of the American Veterinary Medical Association

|November 1, 1978

Summary

This summary is machine-generated.

A maned wolf developed a cystine renal calculus due to an isolated defect in amino acid reabsorption. This condition affected the transport of cystine and other amino acids in the kidneys.

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Abstracts of the 26th International Workshop on Clinical Pharmacology of HIV, Hepatitis and other Antiviral Drugs 2025, 3-4 September 2025, Amsterdam, the Netherlands.

British journal of clinical pharmacology·2025

Same author

700,000 years of tropical Andean glaciation.

Nature·2022

Same author

Conservation of Biodiversity in a Changing Climate.

Conservation biology : the journal of the Society for Conservation Biology·2022

Same author

Mathematically aggregating experts' predictions of possible futures.

PloS one·2021

Same author

Laparoscopic evaluation of the reproductive organs and abdominal cavity content of the lowland gorilla.

American journal of primatology·2020

Same author

Rapid nonlinear bladder and bowel evacuation: an evolutionary survival mechanism?

Techniques in coloproctology·2015

Same journal

Acute-onset neurologic signs in an indoor/outdoor domestic shorthair cat.

Journal of the American Veterinary Medical Association·2026

Same journal

Progressive exophthalmos and strabismus in a 4-year-old Jersey steer.

Journal of the American Veterinary Medical Association·2026

Same journal

Orchiectomy in horses: closed technique and primary closure of the incision.

Journal of the American Veterinary Medical Association·2026

Same journal

Stranguria in a 3-month-old Holstein-Friesian heifer.

Journal of the American Veterinary Medical Association·2026

Same journal

Caudal vena cava-to-aorta ratio in hemodynamically stable and unstable client-owned rabbits.

Journal of the American Veterinary Medical Association·2026

Same journal

Dogs with intrahepatic portal hypertension of congenital cause have distinct diagnostic findings compared to dogs with chronic hepatitis-related portal hypertension.

Journal of the American Veterinary Medical Association·2026

See all related articles

Area of Science:

Veterinary medicine
Nephrology
Amino acid metabolism

Background:

Renal calculi can occur in various species, but cystine calculi are rare.
Understanding renal tubular function is crucial for diagnosing metabolic disorders.

Observation:

An 8-year-old male maned wolf presented with a renal calculus primarily composed of cystine.
Cystine crystals were identified in the animal's urine sediment.

Findings:

The study revealed abnormal renal clearance for 10 amino acids, with cystine, lysine, ornithine, and arginine exceeding the filtered load.
Renal tubular handling of glucose, phosphate, sodium, potassium, and uric acid remained normal, suggesting a specific tubular defect.

Implications:

This case highlights an isolated renal tubular defect affecting amino acid transport in a maned wolf.
The findings contribute to the understanding of metabolic diseases and renal physiology in exotic canids.