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A human milk formula

A Lucas, P J Lucas, S I Chavin

    Early Human Development
    |March 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    A new human milk formula (HMF) enriches preterm infant nutrition by adding human cream and protein to whole human milk. This optimized formula addresses energy and protein deficits in preterm neonates, potentially enhancing immune factors.

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    Area of Science:

    • Neonatal Nutrition
    • Human Milk Research
    • Biochemical Engineering

    Background:

    • Human milk is ideal for neonates but may lack sufficient energy and protein for preterm infants.
    • Low birth weight preterm neonates have specific nutritional requirements that standard human milk may not meet.
    • Existing preterm formulas may not fully replicate the benefits of human milk.

    Purpose of the Study:

    • To develop an enhanced human milk formula (HMF) for low birth weight preterm neonates.
    • To fortify whole human milk with essential nutrients using human milk-derived components.
    • To create a formula that meets the high energy and protein demands of preterm infants.

    Main Methods:

    • Whole human milk was fortified with human cream separated by centrifugation.

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  • Salt-free and lactose-free human milk protein was extracted via dialysis and freeze-drying.
  • These components were added to whole human milk to create the human milk formula (HMF).

    • Main Results:

    • The developed HMF is enriched in energy, human milk fat, protein, and potentially salts.
    • The formula aims to meet the nutritional profile considered ideal for preterm infants.
    • HMF exhibits a higher concentration of antimicrobial proteins, potentially compensating for pasteurization losses.

    Conclusions:

    • The devised human milk formula (HMF) offers a method to enhance the nutritional value of human milk for preterm neonates.
    • This approach provides a bankable, fortified human milk product suitable for vulnerable infants.
    • HMF may offer improved nutritional and immunological benefits compared to standard or pasteurized human milk for preterm infants.