[Comparative analysis of the morphologic and physiologic characteristics of a living isolated neuron]

Close relationship seems to exist among the functional parameters of the neuron membrane and the state of its submembraneous cytoplasm. The study of mollusk neurons deprived of their glial cells showed that the first changes of the cytoplasm occurred in the membrane vicinity, where the aggregation of the cytoplasm proteins occurs. These changes are followed by disappearance of AP and diminishing of membrane potential and resistance of the membrane. The parallel cytoplasmatic and membraneous changes can be due to the interplay of the ionic channels and cytoplasmatic proteins up to their mutual aggregation, and the extraction of proteins from the membrane.