Leiomyosarcoma metastatic to the liver: CT appearance

Area of Science:

• Oncology
• Radiology
• Medical Imaging

Background:

• Leiomyosarcoma is a rare soft-tissue sarcoma.
• Liver and lung metastases are common sites for leiomyosarcoma.
• Accurate detection of liver metastases is critical for patient management.

Observation:

• Computed tomography (CT) characteristics of three leiomyosarcoma liver metastasis cases were analyzed.
• Common imaging findings included hepatomegaly and large, circumscribed "cannonball" lesions.
• Lesions exhibited sharp margins, central necrosis, and contrast enhancement patterns.

Findings:

• Metastases distorted normal liver architecture.
• Larger lesions were enhanced by contrast, surrounding normal liver tissue.
• Smaller metastases could become isodense after contrast administration.

Implications:

• The described CT features suggest metastatic leiomyosarcoma.
• Precontrast scans are vital to avoid underestimating disease extent.
• Radiologists should consider leiomyosarcoma in the differential diagnosis for these imaging findings.