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Weight reduction utilizing a protein-sparing modified fast

S P Yang, L J Martin, G Schneider

    Journal of the American Dietetic Association
    |April 1, 1980
    PubMed
    Summary
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    This study shows that a modified protein-sparing modified fast (PSMF) can lead to significant weight loss in obese patients. Long-term success depends on patient commitment to ongoing therapy and lifestyle changes.

    Area of Science:

    • Clinical Nutrition
    • Obesity Management
    • Metabolic Disorders

    Background:

    • Gross obesity presents significant health challenges, often co-occurring with conditions like diabetes.
    • Effective inpatient and outpatient strategies are crucial for sustainable weight management.

    Purpose of the Study:

    • To evaluate the efficacy of a modified protein-sparing modified fast (PSMF) for weight reduction in severely obese individuals.
    • To assess the impact of inpatient treatment duration and post-discharge support on weight loss outcomes.

    Main Methods:

    • Forty-five grossly obese patients underwent inpatient treatment with a PSMF diet (1.2 gm protein/kg ideal body weight, ~500-800 kcal/day) supplemented with vitamins and minerals.
    • Treatment duration varied (3 days to 2 years), with psychotherapy integrated into the inpatient program.

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  • Post-discharge support included group therapy and regular medical/dietitian appointments.

    • Main Results:

    • Patients achieved significant weight loss during inpatient treatment, ranging from 0.45 to 93.2 kg.
    • Post-discharge weight loss maintenance was challenging, with compliance decreasing despite structured support.
    • Consistent engagement in group therapy correlated with greater success in continued weight loss.

    Conclusions:

    • A modified protein-sparing modified fast is an effective method for substantial inpatient weight loss in obese patients, including those with diabetes.
    • Sustaining weight loss post-discharge requires high patient commitment and adherence to ongoing therapeutic interventions.
    • Long-term success is significantly influenced by continued engagement in supportive therapies like group psychotherapy.