Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Liposarcomas: prognosis and management

C Celik, C P Karakousis, R Moore

    Journal of Surgical Oncology
    |January 1, 1980
    PubMed
    Summary

    Liposarcoma patients frequently experience local recurrence, especially after initial surgery. Adjuvant radiation may be beneficial for liposarcoma treatment when surgical margins are insufficient, potentially improving outcomes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A retrospective cohort study on the efficacy and outcomes of visceral peritonization during laparoscopic Burch colposuspension.

    European journal of obstetrics, gynecology, and reproductive biology·2025
    Same author

    The antitumoral effect of the esculetin in HeLa cells through endoplasmic reticulum stress.

    European review for medical and pharmacological sciences·2024
    Same author

    Prediction of lymph node metastasis based on tumor size in stage 1A endometrioid endometrium cancer.

    European review for medical and pharmacological sciences·2024
    Same author

    The role of shear wave elastography in predicting endometrial cancer in patients presenting with abnormal uterine bleeding.

    European review for medical and pharmacological sciences·2024
    Same author

    Is HPV-negative cervical carcinoma a different type of cervical cancer?

    European review for medical and pharmacological sciences·2023
    Same author

    Lymph node size detected by magnetic resonance imaging for prediction of lymph node involvement in locally advanced cervical cancer.

    European review for medical and pharmacological sciences·2023

    Area of Science:

    • Oncology
    • Surgical Pathology

    Background:

    • Liposarcomas are malignant tumors arising from fat cells.
    • Local recurrence is a significant challenge in liposarcoma management, impacting patient prognosis.

    Purpose of the Study:

    • To analyze local recurrence rates, metastatic patterns, and survival outcomes in liposarcoma patients.
    • To evaluate the impact of primary tumor site and adjuvant radiation on patient survival.

    Main Methods:

    • Retrospective review of 51 evaluable patients with liposarcomas.
    • Analysis of local recurrence rates, sites of metastasis, primary tumor locations, and survival data.
    • Comparison of survival between patients who received adjuvant radiation and those who did not.

    Main Results:

    • A high overall local recurrence rate of 78% was observed.
    • Pulmonary metastases occurred in 45% of patients, and liver metastases in 13.6%.
    • Median survival was significantly better for tumors originating in the extremities compared to other sites (P < 0.01).

    Conclusions:

    • The high incidence of local recurrence in liposarcoma warrants consideration of adjuvant radiation therapy, particularly when surgical margins are inadequate.
    • Early detection and management of local recurrence and metastases are crucial for improving liposarcoma patient outcomes.

    Related Experiment Videos