Subacute sclerosing panencephalitis: clinicopathological study of the eyes

This paper described the clinicopathological findings in a patient who died of subacute sclerosing panencephalitis. During his seven-month hospitalization, we had the opportunity to study the evolution of the disease and especially the variability of the ocular findings. The patient was presenting with a right exotropia and later developed chorioretinal changes in the fundus. The pathological examinations of both eyes revealed undescribed details, mostly in the anterior segments of the eyes, namely lacy vacuolization of the pigment epithelium of the iris, vacuolization of the nonpigmentary ciliary epithelium, and proliferation of the ciliary pigment epithelium.