Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Skull structure with primary cerebellar degeneration

M Spengos, D Vassilopoulos, G Lagos

    Neuroradiology
    |January 1, 1980
    PubMed
    Summary

    Primary cerebellar atrophy is linked to a shallower posterior cranial fossa. This skull structure modification is attributed to shorter clivus and occipital bones in affected individuals.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Haemophagocytic lymphohistiocytosis after intravesical BCG administration for bladder cancer presenting with multiorgan failure.

    Access microbiology·2023
    Same author

    Outcome of refractory to conventional and/or biologic treatment adult Still's disease following canakinumab treatment: Countrywide data in 50 patients.

    Seminars in arthritis and rheumatism·2020
    Same author

    Treatment modalities and drug survival in a systemic sclerosis real-life patient cohort.

    Arthritis research & therapy·2020
    Same author

    The effect of TNF-a antagonists on aortic stiffness and wave reflections: a meta-analysis.

    Clinical rheumatology·2017
    Same author

    Clinical and financial burden of active lupus in Greece: a nationwide study.

    Lupus·2016
    Same author

    Effusive-constrictive pericarditis successfully treated with anakinra.

    Clinical and experimental rheumatology·2015

    Area of Science:

    • Neurology
    • Radiology
    • Anatomy

    Background:

    • Primary cerebellar atrophy is a neurodegenerative condition affecting cerebellar function.
    • Skull morphology, particularly the posterior cranial fossa, may be altered in neurological disorders.
    • Understanding these structural changes can provide insights into disease pathogenesis.

    Purpose of the Study:

    • To investigate the structural characteristics of the posterior cranial fossa in patients with primary cerebellar atrophy.
    • To compare the metric dimensions of the posterior cranial fossa between patients and healthy controls.
    • To explore potential correlations between cerebellar atrophy and specific cranial bone measurements.

    Main Methods:

    • A metric study of skull X-rays was conducted.
    • 13 patients diagnosed with primary cerebellar atrophy were included.
    • Findings were compared to a control group of 100 healthy individuals.

    Main Results:

    • Patients with primary cerebellar atrophy exhibited a significantly shallower posterior cranial fossa compared to controls (p < 0.001).
    • The observed shallowness was associated with reduced bone length, specifically in the clivus and occipital bone (p < 0.01).
    • Statistical analysis confirmed significant differences in posterior fossa dimensions.

    Conclusions:

    • Primary cerebellar atrophy is associated with distinct structural alterations in the posterior cranial fossa.
    • Shortening of the clivus and occipital bone appears to be a key factor contributing to the modified posterior fossa.
    • These findings suggest a potential link between cerebellar degeneration and cranial bone development or remodeling.

    Related Experiment Videos