Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Endolaryngeal neurofibromas

J S Supance, D J Quenelle, J Crissman

    Otolaryngology and Head and Neck Surgery
    |January 1, 1980
    PubMed
    Summary

    Laryngeal neurofibromas are rare, often solitary lesions. Complete initial surgical removal with clear margins is crucial to prevent recurrence, as demonstrated by a challenging case.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Should we kill the case report?

    Veterinary pathology·2008
    Same author

    Foamy gland pattern of pancreatic ductal adenocarcinoma: a deceptively benign-appearing variant.

    The American journal of surgical pathology·2000
    Same author

    "Histiocytic markers" in melanoma.

    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·1999
    Same author

    Screening methods for thyroid hormone disruptors.

    Environmental health perspectives·1999
    Same author

    Recommendations for the reporting of larynx specimens containing laryngeal neoplasms.

    American journal of clinical pathology·1998
    Same author

    Evaluation of epidermal growth factor receptor, transforming growth factor alpha, epidermal growth factor and c-erbB2 in the progression of invasive bladder cancer.

    Urological research·1997

    Area of Science:

    • Otolaryngology
    • Neurosurgery
    • Oncology

    Background:

    • Neurofibromas are benign tumors arising from nerve sheath cells.
    • Laryngeal neurofibromas are exceptionally rare, typically presenting as isolated lesions.
    • Von Recklinghausen's disease (neurofibromatosis type 1) can involve various nerves, but laryngeal manifestation is uncommon.

    Observation:

    • A case of a patient with a persistent endolaryngeal neurofibroma is presented.
    • The patient underwent eight previous surgical attempts for removal.
    • Residual tumor persisted despite multiple interventions.

    Findings:

    • Complete extirpation of laryngeal neurofibromas is challenging.
    • Recurrence is likely if surgical margins are not clear.
    • Frozen section analysis during initial surgery is vital for ensuring complete tumor removal.

    Implications:

    • Emphasizes the need for meticulous surgical technique in managing laryngeal neurofibromas.
    • Highlights the importance of intraoperative frozen section analysis to achieve clear surgical margins.
    • Suggests that incomplete initial resection can lead to multiple reoperations and persistent disease.

    Related Experiment Videos