Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Epithelioid sarcoma. A clinicopathologic and electron microscopic study

M Tsuneyoshi, M Enjoji, N Shinohara

    Acta Pathologica Japonica
    |May 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Urinary N1,N12-diacetylspermine levels correlate with HCV amount in patients with chronic hepatitis C.

    The International journal of biological markers·2017
    Same author

    Expression profiles of genes associated with viral entry in HCV-infected human liver.

    Journal of medical virology·2011
    Same author

    Therapeutic effect of bezafibrate against biliary damage: a study of phospholipid secretion via the PPARalpha-MDR3 pathway.

    International journal of clinical pharmacology and therapeutics·2009
    Same author

    Cyclosporine suppresses cell growth and collagen production in hepatic stellate cells.

    Transplantation proceedings·2006
    Same author

    Urinary N',N'2-diacetylspermine levels correlate with HCV amount in patients with chronic hepatitis C.

    The International journal of biological markers·2005
    Same author

    Clinical significance of urinary N1,N12-diacetylspermine levels in patients with hepatocellular carcinoma.

    The International journal of biological markers·2005

    Epithelioid sarcoma, a rare soft tissue tumor, affects young patients. Despite recurrence and metastasis in some cases, all four patients in this study achieved good outcomes with surgical treatment.

    Area of Science:

    • Oncology
    • Pathology
    • Orthopedic Surgery

    Background:

    • Epithelioid sarcoma is a rare malignant soft tissue tumor.
    • It typically affects young adults and can present with local recurrence and distant metastasis.
    • Clinicopathologic features and treatment outcomes require further elucidation.

    Purpose of the Study:

    • To present a clinicopathologic study of four epithelioid sarcoma cases.
    • To analyze the histological and ultrastructural features of these tumors.
    • To evaluate the treatment outcomes and prognosis of epithelioid sarcoma.

    Main Methods:

    • Retrospective clinicopathologic analysis of four epithelioid sarcoma cases from a cohort of 603 soft tissue sarcomas.
    • Histological examination of tumor morphology, including cellular composition (epithelioid and spindle cells).

    Related Experiment Videos

  • Electron microscopy was performed in two cases to investigate ultrastructural features of tumor cells.

    • Main Results:

    • Four cases of epithelioid sarcoma were identified, representing a small fraction of soft tissue sarcomas.
    • Patients were young, aged 8-21 years, with tumors located in the extremities.
    • Histology showed irregular nodular masses of epithelioid and spindle cells. Electron microscopy revealed a mix of synovioblast-like and fibroblast-like cells.
    • Three patients experienced tumor recurrence, and one had metastases to the skin and regional lymph nodes.
    • All four patients were alive and well at 2-4 year follow-up after surgical intervention.

    Conclusions:

    • Epithelioid sarcoma predominantly affects young individuals and presents with characteristic histological features.
    • Despite potential for recurrence and metastasis, surgical management can lead to favorable long-term outcomes.
    • Further research into the biology and optimal treatment strategies for epithelioid sarcoma is warranted.