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Related Experiment Videos

Parathyroid storm

F Bayat-Mokhtari, G M Palmieri, M Moinuddin

    Archives of Internal Medicine
    |August 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Severe hypercalcemia can cause life-threatening symptoms like seizures and coma. Prompt diagnosis of primary hyperparathyroidism, aided by bone scans, is crucial for timely surgical intervention.

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    Area of Science:

    • Endocrinology
    • Nephrology
    • Neurology

    Background:

    • Primary hyperparathyroidism typically presents with a chronic, mild course.
    • However, acute, severe presentations necessitate urgent diagnosis and surgical intervention.

    Observation:

    • A 71-year-old woman experienced severe hypercalcemia, seizures, and coma refractory to multiple treatments.
    • Normal bone X-rays contrasted with a positive bone scan showing significant soft-tissue uptake.

    Findings:

    • The bone scan findings led to the diagnosis of primary hyperparathyroidism.
    • Surgical removal of a parathyroid adenoma resulted in remarkable recovery and reduced soft-tissue uptake.

    Implications:

    • This case highlights the diagnostic utility of bone scintigraphy in severe hypercalcemia.
  • The authors propose the term
  • parathyroid storm
  • for this rapid, potentially lethal condition requiring immediate surgery.