[Microcirculatory and morphologic disorders following experimental temporary intestinal ischemia]
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Updated: Oct 12, 2026

Murine Model of Intestinal Ischemia-reperfusion Injury
Published on: May 11, 2016
Abstract:
In 30 experimental dogs, microcirculatory and structural changes in the small intestine wall after ligation of the cranial mesenteric artery and restoration of the blood flow in it were followed by vital microscopic and histological examinations. Destructive lesions in the small intestine wall in intestinal ischemia were associated with microcirculatory disorders. Restoration of the blood flow produced an additional inflammatory component which was predominant one week after revascularization. The mucous membrane showed signs of pathological regeneration which by the end of the first month after operation indicated the development of chronic atrophic jejunitis. The microcirculatory bed by the this time returned to normal.

