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Updated: Aug 8, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

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Published on: July 11, 2013

Podophyllum: suspected teratogenicity from topical application

M D Karol, C S Conner, A S Watanabe

    Clinical Toxicology
    |May 1, 1980
    PubMed

    A case demonstrating suspected teratogenic effects of topical podophylium is presented. Podophyllum resin was applied five times for a duration of 4 hr from the 23rd to the 29th week of pregnancy. At birth a simian crease on the left hand and a preauricular skin tag were noted. It is suggested that podophyllum be avoided during pregnancy. Alternative treatment for warts of the vaginal, perineal, or anal area are presented.

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