Therapeutic conization under colposcopic guidance in the operating room

Area of Science:

• Gynecology
• Oncology
• Reproductive Medicine

Background:

• Cervical carcinoma in situ (CIS) is a precancerous condition.
• Fertility preservation is a key concern for young women diagnosed with CIS.
• Therapeutic conization is a standard treatment for cervical intraepithelial neoplasia.

Purpose of the Study:

• To evaluate the efficacy and fertility outcomes of therapeutic conization for cervical carcinoma in situ.
• To assess recurrence rates following fertility-sparing treatment for CIS.

Main Methods:

• One hundred eight patients with satisfactory colposcopy and CIS diagnosis underwent therapeutic conization.
• Procedures were performed under colposcopic guidance in an operating room setting.
• Patients were followed for recurrence and fertility.

Main Results:

• Fifteen of the treated patients conceived, indicating successful fertility preservation.
• One patient experienced recurrence of CIS at 8 months.
• Two patients developed mild dysplasia at 18 and 24 months post-treatment.

Conclusions:

• Therapeutic conization is a viable fertility-sparing option for cervical carcinoma in situ.
• The procedure demonstrates a low recurrence rate and preserves reproductive potential.
• Colposcopically guided conization offers a safe and effective treatment for selected patients.