Proximity of mRNA5'-region and 18S rRNA in eukaryotic initiation complexes

Messenger RNA was covalently linked to 18S ribosomal RNA in eukaryotic 40S and 80S initiation complexes by photoreaction with an RNA cross-linking agent, 4'-substituted psoralen. The sites of interaction of the mRNA capped 5'-region included some 3'-ends of 18S rRNA.