Serum gastrin levels during pregnancy

Serum Gastrin levels were measured by radioimmunoassay in serum samples taken from nongravid normal women and normal healthy pregnant volunteers who were divided into four groups according to gestation time. In nonpregnant control subjects the gastrin values found were 52.23 +/- 2.66 pg/ml. The gastrin levels observed from 5 to 15 and from 36 to 42 weeks of pregnancy are similar to the values of control subjects, whilst the gastrin levels found from 16 to 35 weeks are significantly lower. These results could help us to unravel the distressing problem of dyspeptic symptoms from 16th to 35th week of pregnancy.