The REM cycle is a sleep-dependent rhythm
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Updated: Aug 10, 2026

Polygraphic Recording Procedure for Measuring Sleep in Mice
Published on: January 25, 2016
Abstract:
Two studies, using data from fragmented sleep studies from three sleep laboratories, are reviewed. These studies indicate that the REM cycle is primarily governed by a sleep-dependent oscillator. These data, however, do not rule out the potential influence of endogenous or environmental variables as factors influencing the REM cycle. Further, acceptance of the REM cycle as a sleep-dependent rhythm does not lead to the denial of the basic rest-activity cycle (BRAC) proposed by Kleitman. It is questioned, however, whether the BRAC measured during waking is an extension of the REM cycle recorded during sleep.
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