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Hypercalcaemia in pregnancy: a case report

L P Jensen, G Ras, E G Boes

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |April 26, 1980
    PubMed
    Summary
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    Hypercalcemia during pregnancy in a hypoparathyroid patient caused severe symptoms including neurological issues, pancreatitis, and vision loss. Careful calcium management is crucial for pregnant women with hypoparathyroidism.

    Area of Science:

    • Endocrinology
    • Obstetrics
    • Calcium Metabolism

    Background:

    • Hypoparathyroidism requires careful management, especially during pregnancy.
    • Pregnancy alters calcium homeostasis, increasing risks for certain endocrine conditions.

    Observation:

    • A pregnant patient with hypoparathyroidism on substitution therapy developed severe hypercalcemia.
    • Clinical manifestations included transient cerebral disturbances, acute pancreatitis, and persistent partial blindness.

    Findings:

    • The case highlights the potential for severe hypercalcemia in pregnant hypoparathyroid patients.
    • A postulated mechanism links calcium dysregulation to the observed clinical events.

    Implications:

    • This case underscores the need for vigilant monitoring of calcium levels in pregnant women with hypoparathyroidism.

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  • Findings suggest potential risks and necessitate a review of management strategies for this patient population.