The selective use of systemic antibiotics in the treatment of burns
Abstract:
For the past ten years, we have followed a conservative program in using systemic antibiotics for the treatment of significant burns. Prophylactic antibiotics are not used except for scalds. Antibiotics are given selectively at the time of operation and, otherwise, are reserved for the treatment of specific infections. It has been unusual for a patient with a burn severity index, compatible with survival, to die of uncontrolled sepsis. Resistant bacteria and fungi have not been a problem. We attribute this to the selective use of antibiotics.
Related Concept Videos
Antibiotic Selection
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Combined Effects of Drugs: Synergism
Such synergistic combinations...
Defense Against Bacterial Pathogens
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Acute Pyelonephritis II: Diagnostic Studies and Management
Clinical Significance of Antibiotic Resistance


