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Platelet count on acute induction to high altitude

S C Sharma

    Thrombosis and Haemostasis
    |February 29, 1980
    PubMed
    Summary

    Platelet counts changed differently in healthy volunteers at high altitude. Symptomatic individuals experienced a drop, while asymptomatic individuals showed an increase in platelets.

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    Area of Science:

    • Altitude Medicine
    • Hematology

    Background:

    • High altitude exposure can affect physiological parameters.
    • Platelets play a role in various bodily functions and can be influenced by environmental stressors.

    Purpose of the Study:

    • To investigate the changes in platelet counts in healthy individuals during rapid ascent to high altitude.
    • To compare platelet count trends between symptomatic and asymptomatic individuals at high altitude.

    Main Methods:

    • Fifty healthy volunteers were monitored for platelet counts at sea level and upon rapid ascent to 3658 m.
    • Subjects were categorized into symptomatic and asymptomatic groups based on altitude sickness symptoms.
    • Platelet counts were re-evaluated after returning to sea level.

    Main Results:

    • A decreasing trend in platelet count was observed in the symptomatic group at high altitude.
    • An increasing trend in platelet count was noted in the asymptomatic group at high altitude.

    Conclusions:

    • Platelet count response to high altitude varies between symptomatic and asymptomatic individuals.
    • This suggests a potential link between platelet dynamics and altitude sickness susceptibility.

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