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Related Experiment Videos

[Sinostrial node initial block after digoxin--unmasking by double and multiple stimulation]

H Volkmann, R Paliege

    Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
    |January 1, 1980
    PubMed
    Summary
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    Digoxin administration in a patient with post-myocarditis revealed sinoatrial (SA) block type II. New stimulation methods indicated potential initial SA node block, suggesting altered cardiac conduction.

    Area of Science:

    • Cardiology
    • Electrophysiology
    • Pharmacology

    Background:

    • Myocarditis can lead to cardiac conduction abnormalities.
    • Digoxin is a cardiac glycoside used to treat heart conditions.
    • Assessing sinoatrial conduction time is crucial for understanding heart rhythm.

    Observation:

    • Intravenous digoxin (1 mg) was administered to a patient with a history of myocarditis.
    • Premature atrial stimulation revealed sinoatrial (SA) block type II.
    • Post-extrasystolic pauses remained compensatory even with extremely premature stimuli.

    Findings:

    • Atrial double and multiple stimulation, a novel method for SA conduction time calculation, resulted in irregular post-stimulation pauses.
    • These irregular pauses suggest an initial sinoauricular node block.

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  • The findings indicate a complex response to digoxin in the context of post-myocarditis conduction disturbances.

    • Implications:

    • This case highlights potential digoxin-induced conduction abnormalities in susceptible patients.
    • Novel stimulation techniques may offer new insights into sinoatrial node function.
    • Further research is needed to elucidate the mechanisms of SA block in post-myocarditis patients.