Screening tests for the detection of bladder cancer

Eighty-one individuals had urine cytologies, urinary carcinoembryonic antigen (CEA) determinations and urinary immunoglobulin levels performed in an effort to evaluate various screening tests for the diagnosis of bladder cancer. Urinary cytologies had a predictive value of 57% in detecting bladder cancer. Urinary CEA was of little value in detecting vesical malignancy. Urinary immunoglobulins, particularly IgG and IgA were significantly elevated in the presence of bladder cancer.