Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pineal synaptic ribbons in blinded rats

K Kurumado, W Mori

    Cell and Tissue Research
    |January 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Bilateral ophthalmectomy in rats initially reduced pineal gland synaptic ribbons but led to full recovery within 4-6 months. This study reveals the pineal gland

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Structures of strong shocks in low-density helium and neon gases.

    Physical review. E·2023
    Same author

    Self-Generated Magnetic and Electric Fields at a Mach-6 Shock Front in a Low Density Helium Gas by Dual-Angle Proton Radiography.

    Physical review letters·2019
    Same author

    Preservation of beam emittance in the presence of ion motion in future high-energy plasma-wakefield-based colliders.

    Physical review letters·2010
    Same author

    Ion acceleration by collisionless shocks in high-intensity-laser-underdense-plasma interaction.

    Physical review letters·2004
    Same author

    Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP).

    Proceedings of the National Academy of Sciences of the United States of America·2001
    Same author

    Induction of IRF-3/-7 kinase and NF-kappaB in response to double-stranded RNA and virus infection: common and unique pathways.

    Genes to cells : devoted to molecular & cellular mechanisms·2001
    Same journal

    Correction to: Integrated morphological analyses of Cladomorphus phyllinus and transcriptomic analysis of Cladomorphus trimariensis provide insights into the cardiac morphophysiology of stick insects (Phasmida: Phasmatidae).

    Cell and tissue research·2026
    Same journal

    Deletion of CEACAM1 does not affect retinal and choroidal morphology or transcriptome.

    Cell and tissue research·2026
    Same journal

    Cardiac α2δ1 C-terminal contributes to left atrial hypertrophy in chronic ischemic heart failure, in association with changes in membrane GluN1 and p-CAMKII/p-HDAC4 signaling.

    Cell and tissue research·2026
    Same journal

    Gill ionocytes of the Lake Magadi tilapia (Oreochromis Alcolapia grahami), an extremophilic teleost native to a highly alkaline environment.

    Cell and tissue research·2026
    Same journal

    Integrated morphological analyses of Cladomorphus phyllinus and transcriptomic analysis of Cladomorphus trimariensis provide insights into the cardiac morphophysiology of stick insects (Phasmida: Phasmatidae).

    Cell and tissue research·2026
    Same journal

    Effects of gestational protein restriction on autophagy dynamics during odontogenesis.

    Cell and tissue research·2026
    See all related articles

    Area of Science:

    • Neuroscience
    • Chronobiology
    • Cell Biology

    Background:

    • The pineal gland regulates circadian rhythms, influenced by light.
    • Synaptic ribbons are crucial for neurotransmitter release in the pineal gland.

    Purpose of the Study:

    • To investigate the impact of bilateral ophthalmectomy on pineal gland synaptic ribbons and their circadian rhythm in female rats.

    Main Methods:

    • Electron microscopy was used to quantify synaptic ribbons and ribbon fields.
    • Rats underwent bilateral ophthalmectomy, with pineal glands analyzed at various postoperative intervals.
    • Circadian rhythmicity was assessed by sampling at 4-hour intervals under controlled light-dark cycles.

    Main Results:

    • Bilateral ophthalmectomy caused a significant, temporary decrease in synaptic ribbons and ribbon fields, reaching a minimum at 1 month.

    Related Experiment Videos

  • Despite the reduction, the circadian rhythm persisted 1 month post-surgery.
  • Complete recovery of synaptic ribbons, ribbon fields, and their circadian rhythm was observed by 6 months after ophthalmectomy.

    • Conclusions:

    • The pineal gland exhibits remarkable resilience and recovery capacity following bilateral ophthalmectomy.
    • Synaptic ribbon numbers and circadian rhythmicity are significantly impacted but ultimately restored, highlighting adaptive mechanisms.