Simultaneous hemodialysis and exchange transfusion in hemolytic uremic syndrome

We report our experience in the acute management of a seven-year-old child with severe hemolytic uremic syndrome. On three separate occasions, acute neurologic signs dramatically resolved during simultaneous exchange transfusion and hemodialysis. The ease with which exchange transfusion may be combined with acute hemodialysis is discussed. In selected cases of hemolytic uremic syndrome with marked neurologic manifestations, exchange transfusion may offer a benefit similar to that reported in adults with thrombotic thrombocytopenic purpura.