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Pelvic kidney in infants and children: experience with 16 cases
Journal of Pediatric Surgery
|August 1, 1980
Insights
Pelvic kidney, a congenital anomaly, often co-occurs with other major malformations. Understanding the developmental role of the mesonephros is key to explaining these associated conditions.
Area of Science:
- Embryology
- Urology
- Developmental Biology
Background:
- Pelvic kidney is a congenital renal anomaly where one or both kidneys are located in the pelvis.
- This condition can be associated with various other congenital malformations, impacting multiple organ systems.
Observation:
- A review of sixteen cases of pelvic kidney treated over 12 years was conducted.
- These cases frequently presented with additional major malformations, including ureteropelvic junction obstruction, vesicoureteral reflux, ectopic ureter, vaginal atresia, and vertebral anomalies.
Findings:
- The study highlights the frequent association of pelvic kidney with other significant congenital anomalies.
- The development and ascent of the kidney are intricately linked to embryonic structures.
Implications:
- The mesonephros and its duct play a critical role in the development of both the renal and Mullerian systems.
- Understanding these embryological origins can provide insights into the pathogenesis of complex congenital anomalies involving the urinary and reproductive tracts.
Abstract:
Sixteen cases of pelvic kidney were treated in the past 12 yr. Some are associated with other major malformations including ureteropelvic junction obstruction, vesicoureteral reflux, ectopic ureter, vaginal atresia, and vertebral anomalies. The pivotal role of the resorbing mesonephros and its duct in Mullerian duct development and in renal development and ascent are considered.