Hyperfunctioning parathyroid carcinoma presenting as acute pancreatitis in pregnancy

Area of Science:

• Endocrinology
• Obstetrics
• Surgical Oncology

Background:

• Hyperparathyroidism in pregnancy is uncommon, typically associated with benign parathyroid adenomas.
• While benign forms cause significant maternal and neonatal complications, parathyroid carcinoma has not been previously reported during pregnancy.
• Parathyroid carcinoma presents a more severe clinical course and prognosis compared to adenomas.

Observation:

• A rare case of a pregnant woman presenting with acute pancreatitis was diagnosed as a hyperfunctioning parathyroid carcinoma.
• This marks the first documented instance of parathyroid carcinoma occurring during pregnancy.

Findings:

• The case involved a hyperfunctioning parathyroid carcinoma presenting as acute pancreatitis in a pregnant patient.
• Management strategies and outcomes for both the mother and infant were detailed.
• A literature review on parathyroid carcinoma findings and management was conducted in the context of this unique case.

Implications:

• This case expands the understanding of rare endocrine emergencies during pregnancy.
• It underscores the importance of considering parathyroid carcinoma in pregnant patients with unexplained pancreatitis.
• Further research is warranted on the management and outcomes of parathyroid carcinoma in pregnancy.