[Blood plasma lipolytic enzymes in experimental hyperlipidemia and atherosclerosis in rabbits]

The activity of blood plasma lipolytic enzymes was studied during the development of experimental hypercholesterolemia and atherosclerosis in rabbits. It is shown that lipoproteinlipase activity in post-heparin blood plasma increases most markedly 6 months after feeding rabbits with cholesterol. The concentration of cholesterol and triglycerides in blood plasma also reaches maximum values in this period. The activity of hepatic triglyceridelipase increases significantly within the same period. In rabbits with experimental atherosclerosis, just as in intact animals, however, the lipolytic activity of post-heparin blood plasma is almost entirely due to lipoproteinlipase.