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Round and oval cones in keratoconus

H D Perry, J N Buxton, B S Fine

    Ophthalmology
    |September 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Advanced keratoconus presents two distinct cone types: round and oval. The oval cone type is linked to more severe corneal damage and contact lens fitting challenges, suggesting different patient care approaches.

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    Area of Science:

    • Ophthalmology
    • Corneal Diseases
    • Histopathology

    Background:

    • Advanced keratoconus manifests in distinct morphological patterns.
    • Two primary cone types, round and oval, are observed in advanced keratoconus.
    • The oval cone is frequently associated with complications like corneal hydrops and scarring.

    Purpose of the Study:

    • To differentiate between round and oval cone types in advanced keratoconus.
    • To correlate clinicopathologic findings with cone morphology.
    • To inform patient care strategies based on cone type.

    Main Methods:

    • Histopathologic review of 23 keratoconus cases (10 round, 13 oval).
    • Analysis of Bowman's membrane integrity and Descemet's membrane ruptures.
    • Comparison of clinicopathologic features between round and oval cone groups.

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    Main Results:

    • The oval cone group exhibited significantly more breaks in Bowman's membrane (10.1 vs. 5.0, P < 0.01).
    • A tendency towards greater pannus formation was noted in the oval group.
    • Increased ruptures in Descemet's membrane were observed in oval cones.

    Conclusions:

    • Recognizing distinct round and oval cone types in advanced keratoconus is crucial.
    • Oval cones are associated with more severe histopathologic damage.
    • Clinicopathologic correlation aids in tailored patient management for keratoconus.