[Testosterone level of blood in androgen-dependent gonadal disorders]

The blood plasma testosterone content was determined by radioimmunological method in patients with hirsutism, premature sexual maturation, false male hermaphroditism, true hermaphroditism, mixed gonad dysgenesis, adrenogenital syndrome, and also in some mothers of patients suffering from intersexualism and in healthy persons. The testosterone concentration proved to depend on clinical manifestations in boys with hyper- and hypogonadism and in girls with adrenogenital syndrome. In intersexual conditions in the presence of mixed gonad dysgenesis the testosterone level was found to be intermediate between the normal values in men and women of the same age. By the testosterone level patients with false male hermaphroditism were divided into two groups: with absolute androgen insufficiency and with disturbed receptor testosterone sensitivity.