[Minimal anticonvulsive doses in the treatment of epilepsy]

Serum level and EEG findings were studied in 40 epileptics treated as outpatients with minimum doses of anticonvulsants as a monotherapy. In all cases, the phenotoin levels were below the therapeutic range, the levels of the barbiturate derivatives were on an average higher, in some cases even in the therapeutical range for this preparation. In spite of considerable EEG changes, freedom from fits over a period of many years was observed when minimum doses of the anticonvulsants were given. The results of the study and the consequences resulting for the practical work are summarised in the form of theses.