Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

SEM of the ciliary processes after paracentesis

D K Dueker, H A Chaudhry

    Scanning Electron Microscopy
    |January 1, 1980
    PubMed
    Summary

    Paracentesis (eye trauma) causes changes in ciliary processes, with aspirin being more effective than nerve block at reducing direct and consensual responses in rabbits.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Argon laser trabeculoplasty and pilocarpine effects on outflow facility in the cynomolgus monkey.

    Journal of glaucoma·2009
    Same author

    Multiple CYP1B1 mutations and incomplete penetrance in an inbred population segregating primary congenital glaucoma suggest frequent de novo events and a dominant modifier locus.

    Human molecular genetics·2000
    Same author

    Mutations in CYP1B1, the gene for cytochrome P4501B1, are the predominant cause of primary congenital glaucoma in Saudi Arabia.

    American journal of human genetics·1998
    Same author

    A gene for primary congenital glaucoma is not linked to the locus on chromosome 1q for autosomal dominant juvenile-onset open angle glaucoma.

    Journal of glaucoma·1996
    Same author

    Muscarinic cholinoceptors in native and cultured human corneal endothelium.

    Current eye research·1993
    Same author

    Stimulation of cell division by argon and Nd:YAG laser trabeculoplasty in cynomolgus monkeys.

    Investigative ophthalmology & visual science·1990

    Area of Science:

    • Ophthalmology
    • Ocular Trauma Research
    • Microscopy Techniques

    Background:

    • Corneal perforation and paracentesis are used to induce controlled ocular trauma.
    • Understanding the physiological and pharmacological responses to ocular trauma is crucial.
    • Prostaglandin is a known mediator of the paracentesis reaction.

    Purpose of the Study:

    • To investigate changes in rabbit ciliary processes following paracentesis using scanning electron microscopy (SEM).
    • To examine the consensual response in the contralateral eye after induced ocular trauma.
    • To evaluate the efficacy of aspirin and nerve block in mitigating direct and consensual responses to paracentesis.

    Main Methods:

    • Scanning electron microscopy (SEM) was employed to visualize ciliary process morphology.
    • Controlled ocular trauma was induced via paracentesis in rabbit eyes.
    • Aspirin and local anesthesia (nerve block) were administered prior to trauma to assess their effects.
    • Both the traumatized and the contralateral (fellow) eyes were examined.

    Main Results:

    • Paracentesis induced demonstrable changes in the ciliary processes, observable via SEM.
    • A consensual response was observed in the untreated fellow eye.
    • Aspirin demonstrated greater efficacy than local anesthesia in blocking the direct response to trauma.
    • Both aspirin and nerve block treatments were effective in reducing the consensual response.

    Conclusions:

    • SEM is a sensitive tool for evaluating ocular trauma responses.
    • Ocular trauma can elicit both direct and consensual reactions.
    • Pharmacological interventions like aspirin and nerve blocks can modulate the response to ocular trauma, impacting both direct and consensual effects.

    Related Experiment Videos