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Choroid plexus papilloma: hydrocephalus and cerebrospinal fluid dynamics
Surgical Neurology
|June 1, 1980
Summary
This study measured cerebrospinal fluid dynamics in a hydrocephalus patient with a choroid plexus papilloma. Findings indicate hydrocephalus resulted from fourth ventricle obstruction, not cerebrospinal fluid overproduction.
Area of Science:
- Neurosurgery
- Neurology
- Cerebrospinal Fluid Dynamics
Background:
- Hydrocephalus is often associated with tumors like choroid plexus papilloma.
- Understanding cerebrospinal fluid (CSF) dynamics is crucial for managing hydrocephalus.
Observation:
- CSF production rate, absorption, and critical opening pressure were measured pre- and postoperatively.
- Measurements were taken in a patient diagnosed with choroid plexus papilloma causing hydrocephalus.
Findings:
- Preoperative CSF production: 0.35 ml/min, absorption: 0.0057 ml/min/mm H2O, critical opening pressure: 196 mm H2O.
- Postoperative CSF production: 0.32 ml/min, absorption: 0.0053 ml/min/mm H2O, critical opening pressure: 105 mm H2O.
- No evidence of CSF overproduction was found; hydrocephalus was attributed to fourth ventricle obstruction.
Implications:
- Surgical removal of choroid plexus papilloma effectively reduced CSF pressure.
- This case highlights that hydrocephalus can stem from localized CSF flow obstruction.
- Accurate CSF dynamics assessment aids in determining hydrocephalus etiology and treatment strategies.