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Skin absorption and protective gloves in dynamite work

C Hogstedt, R Ståhl

    American Industrial Hygiene Association Journal
    |May 1, 1980
    PubMed
    Summary
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    Skin absorption is a primary route for ethylene glycol dinitrate (EGDN) exposure in dynamite manufacturing. Protective gloves offer limited protection, highlighting the need for improved biological monitoring and safety gear.

    Area of Science:

    • Occupational Health
    • Toxicology
    • Industrial Hygiene

    Background:

    • Dynamite manufacturing poses serious health risks, with unresolved issues in biological monitoring and protective clothing.
    • Ethylene glycol dinitrate (EGDN) is a key component of concern in dynamite production.

    Purpose of the Study:

    • To investigate the routes of EGDN absorption in dynamite manufacturing workers.
    • To evaluate the effectiveness of protective gloves in preventing EGDN exposure.
    • To assess the utility of blood and exhaled air analysis for biological monitoring.

    Main Methods:

    • Subjects' hands were exposed to dynamite vapors and/or solid phase, with and without various glove types.
    • Ethylene glycol dinitrate (EGDN) levels were measured in blood samples from cubital veins.

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  • Exhaled air was analyzed for EGDN during high exposure periods.
  • Main Results:

    • Skin absorption was identified as a major route of EGDN entry into the body.
    • Rubber gloves absorbed significant EGDN and allowed it to permeate to the skin and blood.
    • Combined rubber and cotton gloves, changed frequently, offered some protection compared to cotton gloves or bare hands.
    • Blood EGDN levels primarily reflected local skin absorption, not total body uptake.
    • No EGDN was detected in exhaled air even during high skin exposure.

    Conclusions:

    • Skin absorption is a critical exposure pathway for EGDN in dynamite manufacturing.
    • Current protective gloves provide inadequate protection against EGDN.
    • Further research is needed for effective biological monitoring and development of superior protective materials.