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Related Experiment Videos

Pancuronium and abnormal abdominal roentgenograms

R G Dillard, J E Crowe, T E Sumner

    American Journal of Diseases of Children (1960)
    |September 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

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    Pancuronium bromide in ventilated infants reduces pneumothorax risk by preventing air swallowing, leading to a "gasless abdomen." This finding helps clinicians avoid unnecessary X-rays in infants receiving pancuronium.

    Area of Science:

    • Neonatal Medicine
    • Pediatric Critical Care
    • Pharmacology

    Background:

    • Mechanically ventilated infants often face risks like pneumothorax.
    • Pancuronium bromide is used in critically ill infants for ventilation.
    • The
    • gasless abdomen
    • is an observed radiographic finding in some infants.

    Observation:

    • Infants treated with pancuronium bromide showed significantly less bowel gas on abdominal X-rays.
    • 22 of 24 pancuronium-treated infants had diminished or absent bowel gas compared to 4 of 14 untreated infants.
    • This
    • gasless abdomen
    • phenomenon was noted in mechanically ventilated infants.

    Findings:

    Related Experiment Videos

    • Pancuronium bromide administration in infants is associated with reduced pneumothorax incidence.
    • The drug prevents air swallowing but does not halt gut peristalsis, causing gas evacuation.
    • No significant differences in birth weight, mortality, or respiratory distress syndrome were observed between groups.

    Implications:

    • Clinicians should recognize the
    • gasless abdomen
    • as a common effect of pancuronium bromide.
    • Awareness of this finding can prevent unnecessary diagnostic imaging in infants.
    • Understanding pancuronium's effect on abdominal gas aids in accurate radiographic interpretation.