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Fused inflammatory polyps simulating carcinoma in ulcerative colitis
The American Journal of Gastroenterology
|May 1, 1980
Summary
A woman with ulcerative colitis developed a large colon polyp. Pathologic examination revealed a unique lesion of filiform polyps trapping a fecal mass, not colon cancer.
Area of Science:
- Gastroenterology
- Colorectal Surgery
- Gastrointestinal Pathology
Background:
- Ulcerative colitis (UC) is a chronic inflammatory bowel disease.
- Colon polyps can be associated with increased risk of colorectal cancer.
- Large polypoid lesions in UC patients warrant thorough investigation.
Observation:
- A 33-year-old female with a decade of ulcerative colitis presented with a large polypoid filling defect in the distal transverse colon.
- Initial biopsy suggested an inflammatory polyp, but the radiographic appearance and patient history prompted subtotal colectomy.
Findings:
- Pathologic examination revealed an unusual aggregation of filiform polyps.
- These filiform polyps had entrapped a semisolid fecal mass.
- The lesion was not indicative of colorectal carcinoma.
Implications:
- This case highlights a rare colonic manifestation in ulcerative colitis.
- It underscores the importance of integrating clinical, radiographic, and pathologic findings for accurate diagnosis.
- Understanding the development of such unique lesions can refine diagnostic and management strategies for inflammatory bowel disease.