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Oxacillin-induced pseudomembranous colitis

R J Friedman, I E Mayer, J T Galambos

    The American Journal of Gastroenterology
    |May 1, 1980
    PubMed
    Summary
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    Pseudomembranous colitis can occur with antibiotic use. This case documents pseudomembranous colitis caused by oxacillin, with the specific bacteria and toxin identified in the patient's stool.

    Area of Science:

    • Microbiology
    • Gastroenterology
    • Pharmacology

    Background:

    • Antibiotic-associated pseudomembranous colitis is a known complication.
    • Various antibiotics have been implicated in its development.

    Observation:

    • A patient developed pseudomembranous colitis after receiving oxacillin therapy.
    • The causative organism and its associated toxin were isolated from the patient's stool sample.

    Findings:

    • This study presents the first documented case of oxacillin-induced pseudomembranous colitis.
    • Identification of the specific bacterial species and toxin responsible for the condition.

    Implications:

    • Highlights the potential for oxacillin to cause pseudomembranous colitis.

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  • Emphasizes the importance of considering oxacillin as a potential cause in antibiotic-associated colitis.
  • Contributes to understanding the spectrum of antibiotic-induced gastrointestinal complications.