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Oxacillin-induced pseudomembranous colitis

R J Friedman, I E Mayer, J T Galambos

    The American Journal of Gastroenterology
    |May 1, 1980
    PubMed

    Insights

    Pseudomembranous colitis can occur with antibiotic use. This case documents pseudomembranous colitis caused by oxacillin, with the specific bacteria and toxin identified in the patient's stool.

    Area of Science:

    • Microbiology
    • Gastroenterology
    • Pharmacology

    Background:

    • Antibiotic-associated pseudomembranous colitis is a known complication.
    • Various antibiotics have been implicated in its development.

    Observation:

    • A patient developed pseudomembranous colitis after receiving oxacillin therapy.
    • The causative organism and its associated toxin were isolated from the patient's stool sample.

    Findings:

    • This study presents the first documented case of oxacillin-induced pseudomembranous colitis.
    • Identification of the specific bacterial species and toxin responsible for the condition.

    Implications:

    • Highlights the potential for oxacillin to cause pseudomembranous colitis.
    • Emphasizes the importance of considering oxacillin as a potential cause in antibiotic-associated colitis.
    • Contributes to understanding the spectrum of antibiotic-induced gastrointestinal complications.

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