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Related Experiment Videos

Sickle cell anemia and hearing

E M Friedman, G R Herer, N L Luban

    The Annals of Otology, Rhinology, and Laryngology
    |July 1, 1980
    PubMed
    Summary
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    Sickle cell anemia can affect hearing in children. This study found a higher incidence of hearing loss in sickle cell patients, with some cases possibly linked to central nervous system involvement.

    Area of Science:

    • Audiology
    • Hematology
    • Pediatrics

    Background:

    • Sickle cell anemia is a genetic blood disorder.
    • Auditory complications in sickle cell anemia are not well-documented.

    Purpose of the Study:

    • To investigate the prevalence of hearing loss in children with sickle cell anemia.
    • To explore potential links between hearing deficits and central nervous system involvement in these patients.

    Main Methods:

    • Audiologic and otologic examinations were conducted.
    • 43 children (ages 7-18) with sickle cell anemia were compared to 23 age-matched controls.

    Main Results:

    • 88% of sickle cell patients had normal hearing; 12% exhibited mild high-frequency sensorineural hearing loss.

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  • No hearing loss was observed in the control group.
  • Three of five patients with hearing loss showed signs of central nervous system involvement (p < 0.025).

    • Conclusions:

    • Children with sickle cell anemia have a higher incidence of hearing loss than controls.
    • Periodic hearing evaluations are recommended for early detection of auditory complications and potential CNS involvement.