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Related Experiment Videos

Ileal meconium plugs

V C Talwalker, D H Kittur

    Archives of Disease in Childhood
    |April 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Neonatal intestinal obstruction can be caused by a white ileal meconium plug, often leading to serious complications. This condition requires careful diagnosis and management, differing from distal meconium plugs.

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    Area of Science:

    • Neonatalogy
    • Pediatric Surgery
    • Gastroenterology

    Background:

    • Neonatal intestinal obstruction is a critical condition requiring prompt diagnosis and intervention.
    • Meconium plugs in the distal colon or rectum are generally benign and treatable with enemas.
    • Ileal meconium plugs represent a distinct clinical entity with potentially severe outcomes.

    Purpose of the Study:

    • To describe the clinical presentation and outcomes of neonatal intestinal obstruction due to white ileal meconium plugs.
    • To differentiate ileal meconium plug syndrome from more distal meconium impactions.
    • To advocate for a refined definition of meconium plug syndrome.

    Main Methods:

    • Retrospective case series analysis of eleven neonates with ileal meconium plugs.

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  • Review of clinical data, including presentation, complications, and treatment outcomes.
  • Comparison with historical data on distal meconium plugs.

    • Main Results:

    • Six of eleven neonates presented with severe complications, including giant meconium pseudocyst, perforation, volvulus, and atresia.
    • Most complications were presumed to have developed antenatally.
    • Only one patient's obstruction was resolved with enemas; others required surgical intervention.
    • Ileal meconium plugs were associated with a higher morbidity than distal meconium plugs.

    Conclusions:

    • White ileal meconium plugs can cause severe neonatal intestinal obstruction and complications, often originating in utero.
    • The term 'meconium plug syndrome' should be reserved for cases of white, chalky meconium plugs relieved by enemas without long-term sequelae.
    • Ileal meconium plugs represent a more serious condition than distal meconium impactions, necessitating distinct clinical consideration.