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Related Experiment Videos

Computerized tomography in multiple sclerosis

T Reisner, E Maida

    Archives of Neurology
    |August 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Computerized tomography (CT) detected 39% of clinically predicted multiple sclerosis (MS) lesions. CT also revealed asymptomatic lesions and atrophy, aiding MS diagnosis.

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    Area of Science:

    • Neurology
    • Radiology

    Background:

    • Multiple sclerosis (MS) diagnosis relies on clinical evaluation and imaging.
    • Discrepancies between clinical findings and imaging are common.

    Purpose of the Study:

    • To compare clinical predictions of cerebral lesions with computerized tomography (CT) findings in multiple sclerosis (MS) patients.
    • To assess the utility of CT in identifying asymptomatic lesions and atrophic changes.

    Main Methods:

    • Clinical examination of 43 multiple sclerosis (MS) patients.
    • Computerized tomography (CT) scans to identify cerebral lesions.
    • Correlation analysis between clinical predictions, CT findings, disease duration, and previous bouts.

    Main Results:

    • CT confirmed 31 (39%) of 80 clinically predicted focal cerebral lesions.

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  • CT identified 17 atypical periventricular lesions and 18 asymptomatic focal lesions.
  • A significant relationship was found between disease duration and the number of CT foci, but not with previous bouts.
  • Cerebral atrophy was observed in 15 patients, unrelated to disease duration or bouts.

    • Conclusions:

    • Computerized tomography (CT) provides valuable additional information beyond clinical examination in multiple sclerosis (MS).
    • CT can detect asymptomatic lesions and aid in diagnosing challenging or early MS cases.
    • CT findings correlate with disease duration, suggesting its role in monitoring disease progression.