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Updated: Aug 13, 2026

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
Published on: July 4, 2007
Acute disseminated encephalomyelitis after influenza vaccination
Abstract:
A 12-year-old, previously healthy boy was seen with typical signs of acute disseminated encephalomyelitis four days after influenza vaccination. Computerized tomography demonstrated an extensive subcortical low-density area in the left cerebral hemisphere. The CSF contained elevated levels of immunoglobulins, especially IgG, and an abnormal kappa:lambda chain ratio. Skin tests for hypersensitivity to egg protein were negative, but reaugmentation of CSF protein and immunoglobulin levels was observed within ten days after skin tests.
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