[Relationship between the breakdown voltage of bilayer lipid membranes and the rate of potential difference increase]

Electrical breakdown of bilayer lipid membranes from glycerol monooleate at voltage scanning velocity from 0.01 V/s to 500 V/s was considered. It has been shown that up to the rates 0.1 V/s the disruption of films takes place at 200--250 mV, and at scanning rates above 1 V/s -- at 500--600 mV. It is suggested that the electric breakdown of the membrane is realized via different mechanisms depending on the rate of the electric field change.