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Updated: Aug 18, 2026

Pre-Conditioning the Airways of Mice with Bleomycin Increases the Efficiency of Orthotopic Lung Cancer Cell Engraftment
Published on: June 28, 2018
Tumorigenic effect of topical mechlorethamine, BCNU and CCNU in mice
Abstract:
Mice were painted with mechlorethamine (HN2), carmustine (BCNU) and lomustine (CCNU) for up to 33 weeks. HN2 was a potent carcinogen, producing squamous cell carcinomas in 9 of 33 mice in 1 series. BCNU was a weak carcinogen. CCNU produced no tumors in 1 series.
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