Genetic influence in the development of obesity: focus on food intake

Three areas are identified as important for the genetic influence on the development of obesity, focusing on food intake. (1) Contribution of hyperinsulinemia to the development of hyperphagia and obesity in genetically obese animals. (2) Manipulation of quantity of food intake at various ages in animals. (3) Influence of exercise not only on food intake but on metabolism in the long term.