Cervical stenosis following minor gynecologic procedures on DES-exposed women

The findings associated with diethytlstilbestrol (DES) exposure in utero are expanding rapidly. Structural abnormalities in both the cervix and uterus are well documented; in addition the authors have noted indications of an abnormal healing response in these women. Locally destructive methods such as cryosurgery, cauterization, and excision have resulted in permanent and significant physical damage. Caution is advised in attempting even minor gynecologic procedures on DES-exposed offspring.