A new low-concentration preparation for mydriasis and cycloplegia

This study was designed to evaluate a low-concentration, cycloplegic-mydriatic mixture of phenylephrine and tropicamide in a routine office examination. No clinically significant difference in pupillary dilation was found between the usual instillation of the standard, commercially available phenylephrine 10% and tropicamide 1% drops and the prepared, low-concentration solution. Pupillary dilation was well maintained during direct and indirect ophthalmoscopy and retinoscopy. This solution is easily prepared from readily available drugs, and is simply delivered to the eye using a standard eye dropper. The safety and effectiveness of this low-concentration mixture of phenylephrine and tropicamide make it strongly recommended for routine use.