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Yersinia enterocolitica Septicemia

E Bouza, A Dominguez, M Meseguer

    American Journal of Clinical Pathology
    |October 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

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    Human Yersinia enterocolitica septicemia is rare, often affecting the young and elderly with underlying conditions. Antibiotic susceptibility patterns are crucial for effective treatment, with resistance to some drugs but sensitivity to others.

    Area of Science:

    • Infectious Diseases
    • Microbiology
    • Clinical Medicine

    Background:

    • Yersinia enterocolitica septicemia is an uncommon but serious infection.
    • This condition disproportionately affects pediatric and geriatric populations.
    • Pre-existing conditions like liver disease, diabetes, and immunosuppression increase risk.

    Observation:

    • Clinical presentation of Yersinia enterocolitica septicemia is often indistinguishable from other Enterobacteriaceae sepsis.
    • A review of 51 cases from literature and four new cases were analyzed.
    • Isolates were tested for antibiotic susceptibility.

    Findings:

    • Yersinia enterocolitica strains typically exhibit resistance to beta-lactam antibiotics.
    • Sensitivity was observed with aminoglycosides and co-trimoxazole.

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  • Notably, isolates showed susceptibility to newer cephalosporins (cefamandole, cefoxitin) and experimental agents (HR-756, T-1551, Ly-127.935).

    • Implications:

    • Awareness of Yersinia enterocolitica as a potential pathogen is critical for timely diagnosis.
    • Understanding specific antibiotic resistance and susceptibility patterns guides effective therapeutic choices.
    • Emerging cephalosporins and experimental antibiotics may offer alternative treatment options for Yersinia enterocolitica infections.