Permanent tooth sizes in 46,XY females

The teeth of seven Finnish patients with complete testicular-feminization syndrome (46,XY females) were studied to obtain further information about their growth and possible somatic determinants on the Y chromosome. The sizes of the permanent teeth of the 46,XY females were found to be as large as those of control males and definitely larger than those of control females. Testicular feminization is caused by androgen insensitivity, and persons affected are phenotypically females. Hence, these results also indicate the influence of the Y chromosome on dental determination.