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Hypertension: a complication of danazol therapy
Archives of Internal Medicine
|October 1, 1980
Summary
Danazol therapy can cause hypertension, a complication not previously documented. This drug-induced hypertension is volume-dependent and manageable with diuretics, necessitating regular blood pressure monitoring for patients.
Area of Science:
- Endocrinology
- Pharmacology
- Nephrology
Background:
- Danazol, a semisynthetic androgen, is prescribed for endometriosis and hereditary angioedema.
- Fluid retention and weight gain are known side effects of danazol.
- Hypertension has not been previously associated with danazol use.