The autoradiographic localization of paraquat in the lung

Paraquat poisoning in mammals results in a characteristic lung lesion manifested principally as progressive pulmonary fibrosis. Paraquat is actively concentrated into the lung but the site of uptake remains undefined. A method is described for the autoradiographic localization of paraquat. Preliminary evidence for the site of uptake implicates the bronchiolar epithelium.