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Related Concept Videos

Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

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Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
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Arteries and Arterioles01:16

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Arteries, the vasculature responsible for transporting blood from the heart, possess robust walls capable of enduring the elevated pressures exerted by the heartbeat. Arteries near the heart are especially thick-walled and enriched with elastic fibers across their three tunics, classifying them as elastic or conducting arteries. These arteries, usually with a diameter exceeding 10 mm, are characterized by their ability to dilate in response to the blood pumped from the heart's ventricles...
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Arteries of Lower Limbs01:20

Arteries of Lower Limbs

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The external iliac artery transitions out of the body cavity, entering the femoral region of the lower leg, and is renamed the femoral artery at the point where it traverses the body wall. This artery is responsible for the distribution of blood to the thigh's deep muscles and the skin's ventral and lateral regions, achieved through several minor branches and the lateral deep femoral artery, which also spawns a lateral circumflex artery. The knee area receives blood from the genicular...
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Arteries of the Upper Limbs01:12

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The subclavian artery transitions into the axillary artery as it exits the chest and enters the axillary region. This artery is critical for supplying blood to the shoulder area, including the head of the humerus, through the humeral circumflex arteries. As the vessel continues into the upper arm or brachium, it becomes the brachial artery. This artery plays a key role in vascularizing the brachial region and bifurcates at the elbow into several branches. These branches include the deep...
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Overview of Systemic Arteries01:11

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The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
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Arteries of the Head and Neck01:26

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The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
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Related Experiment Video

Updated: Jan 24, 2026

Implantation of Tissue-Engineered Vascular Graft in Mouse Carotid Artery via Cuff Technique
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Segmental microvenous graft to artery

S K Das, B M O'Brien, F S Browning

    British Journal of Plastic Surgery
    |July 1, 1980
    PubMed
    Summary

    Microvenous grafts in rabbits showed improved patency rates over time, reaching 100% by 1979. Scanning electron microscopy confirmed no short-term lumen narrowing or microaneurysm formation in these vascular grafts.

    Area of Science:

    • Vascular Surgery
    • Microsurgery
    • Experimental Surgery

    Background:

    • Vascular grafting is crucial for arterial reconstruction.
    • Assessing the long-term efficacy of microvenous grafts is essential.
    • Previous studies have reported potential complications like lumen narrowing.

    Purpose of the Study:

    • To evaluate the patency rates of microvenous grafts over time.
    • To assess the morphological changes in microvenous grafts using scanning electron microscopy.
    • To compare graft performance across different surgical periods.

    Main Methods:

    • 105 microvenous grafts were performed on rabbits (2-2.5 kg) over three periods: 1971, 1975, and 1979.
    • A standard technique involved inserting a 1 cm vein graft into a 0.5 cm femoral artery defect.

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  • Graft patency was assessed from 1 to 21 weeks post-surgery; scanning electron microscopy was used for morphological analysis.

    • Main Results:

    • Patency rates improved significantly: 71% in 1971, 96% in 1975, and 100% in 1979.
    • Scanning electron microscopy revealed no lumen narrowing or microaneurysm formation in the short term.
    • The results indicate a trend of increasing success with microvenous grafting techniques over the study periods.

    Conclusions:

    • Microvenous grafting techniques have demonstrated progressive improvement in patency rates.
    • The study supports the safety and efficacy of microvenous grafts, with no observed short-term adverse morphological changes.
    • These findings suggest that optimized surgical techniques enhance the reliability of vascular grafts.